Relive the medical mysteries of Princeton-Plainsboro with this comprehensive look at . From the introduction of the iconic, Vicodin-dependent diagnostician to the high-stakes showdown with Edward Vogler, the first season laid the groundwork for one of television's most enduring dramas. The Blueprint of a Genius: Gregory House

While many early episodes are episodic "puzzles-of-the-week," a major multi-episode arc defines the latter half of the season:

: Billionaire Edward Vogler (Chi McBride) donates $100 million to the hospital, becoming the new chairman of the board.

: Seeing House as a waste of resources, Vogler attempts to force him into firing a team member and eventually tries to revoke his tenure.

: House is supported by a trio of young specialists— Dr. Eric Foreman (Omar Epps), Dr. Robert Chase (Jesse Spencer), and Dr. Allison Cameron (Jennifer Morrison).

Premiering on November 16, 2004, the first season introduced us to (played by Hugh Laurie), a maverick physician who prioritizes the puzzle over the patient.

: In a dramatic finale, Cuddy risks the hospital's funding by siding with House, leading the board to oust Vogler and reclaim their independence. Essential Episodes for Your Archive

: The prickly genius is constantly at odds with the Dean of Medicine, Dr. Lisa Cuddy (Lisa Edelstein), who struggles to keep him in line while respecting his diagnostic brilliance. Season 1 Story Arc: The Vogler Era