If using a USB cable, ensure the Prolific or Leica USB-to-Serial drivers are installed.
Ensure the baud rate on the total station (usually 19200) matches the software setting. Troubleshooting Common Issues leica survey office 2.21 english download
Match the COM port in the software’s "Communication Settings" to the one assigned by your Windows Device Manager. If using a USB cable, ensure the Prolific
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If the software fails to launch, try running it as an Administrator.