Open Neo Programmer 2.1.0.19 and click the "Detect" (magnifying glass) icon.
Connect your CH341A programmer to your PC. Ensure the drivers are installed (the software usually includes the necessary CH341PAR.SYS drivers).
Reflashing firmware on display controller boards.
If the software fails to detect the chip, the most common culprit is oxidation on the pins. Clean them with isopropyl alcohol.