SPI simulations can be CPU-intensive. Try reducing the "Animation Sampling Rate" in System Settings.
Causing the simulation to crash when the SPI communication starts. rc522 proteus library updated
Once your circuit is wired, you need to upload the Hex file to your Arduino. Use the standard MFRC522.h library in the Arduino IDE. SPI simulations can be CPU-intensive
The RC522 is a highly popular 13.56MHz RFID reader/writer. Earlier versions of Proteus libraries often suffered from: rc522 proteus library updated
Check if you have assigned a Hex file to the Arduino and that the SPI pins are correctly mapped (11, 12, 13).
Inability to "present" a virtual RFID card to the reader.