Classification | Sakitamiwa

Over weeks or months, the redness fades into a white or pale scar as the tissue matures. This marks the final stage of healing. Clinical Utility and Scoring

The ulcer is significantly smaller. The regenerating epithelium covers most of the base, leaving only a tiny central defect. 3. Scarring Stage (S1 & S2)

The ulcer becomes shallower as granulation tissue fills the base. Regenerating epithelium (new skin) begins to creep in from the edges, often creating a "palisade" appearance of mucosal folds. sakitamiwa classification

In modern research, doctors often assign numerical scores to these stages to quantitatively measure improvement. For example, a study on ischemic colitis or Behçet’s disease might use the following scale: Clinical Meaning Numerical Score (Example) Highly Active / Deep A2 Active / Slightly Improved H1 Early Healing H2 Advanced Healing S1 Red Scar (Healed) S2 White Scar (Mature) Why is this Classification Important?

The ulcer base is completely covered by new epithelium, but the area remains red and vascularized. This is a "fresh" scar. Over weeks or months, the redness fades into

This classification is a critical tool in clinical trials to evaluate the efficacy of acid-suppressing drugs like Proton Pump Inhibitors (PPIs) and Potassium-Competitive Acid Blockers (P-CABs) .

At this point, the ulcer is considered "endoscopically cured" because the mucosal defect has vanished. The regenerating epithelium covers most of the base,

This transition indicates that medical treatment or natural recovery is effectively closing the wound.

The edema at the ulcer margin begins to subside, and the ulcer base appears cleaner. The white coating may begin to thin. 2. Healing Stage (H1 & H2)

In this stage, the ulcer is "active" and often associated with the highest risk of complications like bleeding.