The Last Official Driver: The version 2.8.28 (originally for Vista/7) is the most stable starting point. You must run this installer in Compatibility Mode for Windows 7.
If you are looking to breathe new life into your MI4, here is everything you need to know about compatibility, drivers, and setup. The Compatibility Challenge Steinberg Mi4 Windows 10
Compatibility Mode: Right-click the driver installer, go to Properties > Compatibility, and select "Windows 7." The Last Official Driver: The version 2