Collected items and active icons are visible on the lower screen, allowing you to see your current build without pausing.

is a massive remake of the original 2011 Flash-based roguelike, completely overhauled with a new engine and expanded content. While it spans nearly every modern platform, the version for the New Nintendo 3DS stands out as a unique way to experience Isaac’s descent into the basement on a handheld. Essential Version Information

Despite the hardware's power, the 3DS version of Rebirth is known for having some performance trade-offs compared to the PC or modern console versions:

New Nintendo 3DS / New Nintendo 3DS XL / New Nintendo 2DS XL only.

Players can use the lower screen to make notes or even activate certain items. Gameplay and Performance

The Ultimate Guide to The Binding of Isaac: Rebirth on New Nintendo 3DS